Oral drug delivery – typically as tablets or capsules – is the most preferred administration route due to convenience, cost-effectiveness, and high patient compliance.

Unfortunately… These advantages fail to hold when it comes to patients who have dysphagia, a swallowing disorder that results in difficulties ingesting tablets/capsules. 

These difficulties can range from a total inability to swallow to coughing or choking because the medicine ends up entering the windpipe (i.e. aspiration) instead of the food pipe. Medication can also get 'stuck' in the throat – causing significant discomfort.

The act of taking medicines can thus become distressing for patients, who may resort to breaking tablets, crushing and dissolving them in water, or chewing them. While these methods make it easier for patients to get the medicine down, they can negatively affect the release profile and bioavailability of biologically active ingredients in the pills/capsules. This can then decrease the medicine's efficacy. Perhaps most worryingly: some patients would rather skip out on taking their medication entirely because of how unpleasant the entire experience is.

Medication nonadherence is a serious problem, with consequences including worsening conditions, increased comorbid diseases, increased health care costs, and even death. Here at biosyn, we believe that there are better ways of administering life-saving medications that boost therapeutic outcomes – drugs that are easier to swallow; treatments that are much more pleasant for individuals struggling with dysphagia.

That’s why we’re committed to producing products that are easier to take for all patients, no matter their swallowing capabilities.